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Objective@#To explore the clinical effect of percutaneous low frequency electric stimulation on prevention of venous indwelling needle thrombotic blockage in patients with coronary heart disease.@*Methods@#A total of 150 patients admitted to the department of cardiovascular medicine from May 2017 to January 2018 who met the inclusion and exclusion criteria were selected. It was divided into the intervention group and the control group by the random number table method, including 75 cases in the intervention group and 75 cases in the control group. In the control group, the routine nursing method was adopted for the maintenance of intravenous indwelling needle. In the intervention group, on the basis of routine nursing, the percutaneous low frequency electrical stimulation was added. The incidence of thrombosis, occlusion, mean retention time, patient satisfaction and intravenous infusion complications were compared between the two groups.@*Results@#The incidence of thrombosis was 40.0% (30/75) and64.0% (48/75) in the intervention group and the control group, and the blockage rate was 28.0% (21/75) and 52.0% (39/75) in the intervention group and the control group, respectively. There were significant differences between the two groups (χ2=8.654, 9.000, all P< 0.01). The incidence of phlebitis, drug exosmosis and subcutaneous bruising were 13.33% (10/75), 13.33% (10/75) and 18.67% (14/75) in the intervention group, 33.33% (25/75), 40.00% (30/75) and 41.33% (31/75) in the control group, respectively. There were significant differences between the two groups (χ2 = 8.385, 13.636, 9.175, all P< 0.01). The indwelling time and patient satisfaction of the intervention group were (2.817±0.221) d and 82.67% (62/75) respectively, while those of the control group were (2.291±0.127) d and 50.67% (38/75), respectively. There were significant differences between the two groups (t=17.926, χ2=17.280, all P<0.01).@*Conclusions@#Percutaneous low frequency electrical stimulation has positive significance for improving the formation of thrombus at the point of intravenous indwelling needle and preventing the blockage of catheter caused by thrombosis.
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Objective To explore the clinical effect of percutaneous low frequency electric stimulation on prevention of venous indwelling needle thrombotic blockage in patients with coronary heart disease. Methods A total of 150 patients admitted to the department of cardiovascular medicine from May 2017 to January 2018 who met the inclusion and exclusion criteria were selected. It was divided into the intervention group and the control group by the random number table method, including 75 cases in the intervention group and 75 cases in the control group. In the control group, the routine nursing method was adopted for the maintenance of intravenous indwelling needle. In the intervention group, on the basis of routine nursing, the percutaneous low frequency electrical stimulation was added. The incidence of thrombosis, occlusion, mean retention time, patient satisfaction and intravenous infusion complications were compared between the two groups. Results The incidence of thrombosis was 40.0% (30/75) and 64.0% (48/75) in the intervention group and the control group, and the blockage rate was 28.0% (21/75) and 52.0% (39/75) in the intervention group and the control group, respectively. There were significant differences between the two groups (χ2=8.654, 9.000, all P< 0.01). The incidence of phlebitis, drug exosmosis and subcutaneous bruising were 13.33% (10/75), 13.33% (10/75) and 18.67% (14/75) in the intervention group, 33.33% (25/75), 40.00% (30/75) and 41.33% (31/75) in the control group, respectively. There were significant differences between the two groups (χ2=8.385, 13.636, 9.175, all P<0.01). The indwelling time and patient satisfaction of the intervention group were (2.817 ± 0.221) d and 82.67% (62/75) respectively, while those of the control group were (2.291±0.127) d and 50.67% (38/75), respectively. There were significant differences between the two groups (t=17.926, χ2=17.280, all P<0.01). Conclusions Percutaneous low frequency electrical stimulation has positive significance for improving the formation of thrombus at the point of intravenous indwelling needle and preventing the blockage of catheter caused by thrombosis.
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OBJECTIVE: To assess the effectiveness of our devised hybrid physiotherapy regime using an anti-gravity treadmill and a low-frequency electrical stimulation device, as measured in patients with hip osteoarthritis after total hip arthroplasty (THA). METHODS: The outcomes of the postoperative rehabilitation in 44 patients who underwent THA for hip osteoarthritis were retrospectively examined. The conventional group (n=22) underwent the postoperative rehabilitation according to our protocol, while the hybrid group (n=22) underwent the same training, along with training on an anti-gravity treadmill and training using a low-frequency therapeutic device. The outcome measures were recorded and reviewed with the Numerical Rating Scale for pain, which rates pain on an 11-point scale from 0 to 10, surgical side knee joint extension force, 10-m walking test, Timed Up and Go test, and the 6-minute walking distance (6MD). The outcome measurement was taken 2 weeks after conducting pre-operation and antigravity treadmill training and electrical muscle stimulation, and compared the respective results. RESULTS: At the timeframe of 2 weeks from the surgery after conducting a devised hybrid physiotherapy, the values of knee extension muscle strength and 6MD were not worse in the hybrid group than conventional group. In the evaluation at 2 weeks after surgery, the knee extension muscle strength and 6MD values significantly decreased compared with the preoperative values only in the conventional group. CONCLUSION: Lower limb muscular strength and endurance were maintained in the hybrid group, which suggested that hybrid physiotherapy could maintain physical functions early after THA operation.
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Humans , Arthroplasty, Replacement, Hip , Electric Stimulation , Follow-Up Studies , Knee , Knee Joint , Lower Extremity , Muscle Strength , Osteoarthritis, Hip , Outcome Assessment, Health Care , Rehabilitation , Retrospective Studies , WalkingABSTRACT
Objective To explore the effect of oral sensorimotor therapy (OSMT), acupuncture, and low frequency electrical stimulation on salivation in patients with cerebral palsy. Methods From September, 2014 to October, 2015, 80 cerebral palsy patients with salivation were recruited. They were randomly divided into four treatment groups:group A was treated with OSMT, group B was treated with acupunc-ture, group C was treated with frequency electrical stimulation, and group D was treated with acupuncture and low frequency electrical stim-ulation, for eight weeks. Meanwhile, 20 cerebral palsy patients with salivation from outpatients were chosen as control group. Results There was no improvement in the root mean square (RMS) value of surface electromyography (sEMG) after treatment in both the control group and group A (t0.05), and the RMS value significantly improved in the groups B, C and D (t>8.983, P0.05), and they was better in the groups B, C and D than in the control group and group A (W>226.0, t>8.534, P306.0, t>3.663, P<0.05). Conclusion Acupuncture and low frequency electrical stimulation could effectively improve salivation in children with cerebral palsy, and their combination was superior to either ones, while OSMT did not show obvious benefit.
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Objective To study the effect of low frequency electrical stimulation on blood hormone levels in differ -ent animals.Methods At 12 h, 24 h and 36 h after low frequency electrical stimulation to Chinese tree shrews , Wistar rats, and BALB/c mice, respectively, the blood noradrenaline (NA) and endothelin (ET) levels were determined by ra-dioimmunoassay ( RIA) .Results The blood NA and ET levels of electrical stimulation group were significantly higher than that in the control group (P Wistar rats >BALB/c mice.Conclusions Low frequency electrical stimulation can promote the release of noradrenaline and en -dothelin in Chinese tree shrews , Wistar rats and BALB/c mice.Reserpine can reduce the stress induced by low frequency electric stimulation to the body .
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@#A varus dropped foot, one of the most common deformities of hemiplegic lower limb in stroke patients, significantly affected the ability of ambulation. Electric stimulation therapy was one of mostly used techniques for this problem. This paper focused on the application of low frequency electric stimulation in the treatment of the varus dropped foot in stroke patients, analyzed the clinical efficacy and advantage of neuromuscular electrical stimulation and functional electrical stimulation, and the discussion of their mechanism.
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Objective To observe the clinical efficacy of flexor-extensor alternate electroacupuncture with low-frequency stimulation in improving the wrist-hand function after high spinal cord injury.Method Forty patients with high spinal cord injury were randomized into a treatment group and a control group, 20 cases in each group. The treatment group was intervened by flexor-extensor alternate electroacupuncture with low-frequency stimulation, while the control group was by electroacupuncture. The Lindmark score, MAX and IEMG of sEMG were observed before and after intervention, and the clinical efficacies were compared between the two groups.Result The MAX, IEMG of sEMG and Lindmark scores were significantly changed after the treatment in both groups (P<0.05). The sEMG signal values and Lindmark score of the treatment group were significantly different from that of the control group after the treatment (P<0.05). The total effective rate was 95.0% in the treatment group versus 80.0% in the control group, and the difference was statistically significant (P<0.05).Conclusion Flexor-extensor alternate electroacupuncture with low-frequency stimulation is an effective method in improving the wrist-hand function after high spinal cord injury.
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A varus dropped foot, one of the most common deformities of hemiplegic lower limb in stroke patients, significantly affected the ability of ambulation. Electric stimulation therapy was one of mostly used techniques for this problem. This paper focused on the applica-tion of low frequency electric stimulation in the treatment of the varus dropped foot in stroke patients, analyzed the clinical efficacy and ad-vantage of neuromuscular electrical stimulation and functional electrical stimulation, and the discussion of their mechanism.
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Objective To test the efficacy of low-frequency electrical acupoint stimulation plus rehabilitation training in improving swallowing function after stroke. MethodsEighty dysphagic stroke patients were randomly allocated into 2 groups of 40.Patients in the experimental group received low-frequency electrical acupoint stimulation plus 2 courses of rehabilitation training.Control group patients received the same protocol,but the electrical stimulation was not over acupoints.Their swallowing function was assessed using the Kubota water drinking test.ResultsAfter treatment,both groups showed significantly lower Kubota scores compared with pre-treatment.Prepost test difference was 1.25 ± 0.78 in the experimental group and 0.70 ± 0.72 in the control group,a significant difference.The total recovery rate in the experimental group was 87.5％.In the control group it was 55％.The improvement in swallowing function was significantly better in the experimental group.Conclusion Both groups showed a significant improvement in swallowing function,but low-frequency electrical acupoint stimulation increased the effectiveness of the rehabilitation training.
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@#Objective To observe the effect of low frequency electrical stimulation on dysphagia after stroke. Methods 60 patients with dysphagia after stroke were divided into treatment group and control group with 30 cases in each group. The control group was treated with swallowing exercise, while the treatment group was treated with low frequency electrical stimulation in addition. They were assessed with Fujishima's swallowing evaluation before and after treatment. Results The score increased after treatment in both groups (P<0.05), and increased more in the treatment group than in the control group (P<0.05). Conclusion Low frequency electrical stimulation can improve the effects of swallowing exercise on dysphagia after stroke.
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Objective To assess the efficacy of low-frequency electrical stimulation (LES) in improving ability in the activities of daily living (ADL) of subjects after a recent stroke. Methods In a randomized controlled trial, 37 subjects with a first stroke were randomly divided into an electrical stimulation (ES) group and a control group. In the ES group (n = 19 ) electrodes were applied on the motor points of the tibialis anterior, the peroneal longus and the peroneus brevis muscles. Stimulation current was applied at an intensity set to cause full ankle extension. The stimulus pulse was a symmetric biphasic wave with frequency of 30 Hz, a pulse width of 200 μs, a duty cycle of 5 s on and 5 s off ramped up and down for 1 s each and amplitude up to 90 mA. The current amplitude was adjusted according to each subject's comfort. Stimulation lasted for 30 min/d, 5 d/week for 3 weeks. All subjects in the 2 groups also received a standard rehabilitation program. Evaluations included the Fugl-Meyer motor assessment (FMA) for the lower extremity and the modified Barthel index (MBI) for ADL ability. Measurements were recorded before treatment and after 2 and 3 weeks of treatment. Results Before treatment there was no significant difference between the two groups in terms of age, time post-stroke, stroke severity or the baseline measurements. After 2 and 3 weeks of treatment, the FMA scores in the ES group were significantly higher than those of the control group. The MBI scores in the ES group were also significantly higher than in the control group. The average MBI transferring, walking and stair climbing scores in the ES group were all significantly higher than those in the control group after either 2 or 3 weeks. Conclusion Three weeks of LES can improve ADL ability soon after stroke.
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Objective To observe the effects of low frequency electrical stimulation (LFES) on the proliferation of endogenous brain neural stem cells (NSCs) and on the expression of basic fibroblast growth factor (bFGF)and epidermal growth factor (EGF) in rats with acute cerebral infarction; to explore the therapeutic mechanism of LFES in improving neural function. Methods Fifty-four rats were randomly divided into a LFES group, a placebo stimulation group and a sham-operated group. Each group was further divided into 3rd day, 7th day and 14th day subgroups, with 6 rats in each subgroup. An acute cerebral infarction model was induced in the rats of the LFES and placebo stimulation groups by middle cerebral artery occlusion (MCAO). Three days after the operation, rats in the LFES group began LFES treatment (frequency 30 Hz, pulse width 250 μs, current intensity 3 mA, 10 min/d) ,while the placebo stimulation group was treated identically but without electricity. The rats in the sham-operated group had no special treatment. The expression of nestin positive cells in the subgranular zone of the hippocampus and the subventricular zone was detected by immunohistochemical staining. The expression of bFGF, EGF proteins and mRNA in the ischemic hemisphere was detected by Western blotting and RT-PCR analysis. A screen test was applied to evaluate motor function. Results Nestin-positive cells in the subgranular and subventricular zones of rats in the LFES group increased significantly more than in the placebo stimulation group at the 7th and 14th day. The expression of bFGF, EGF proteins and mRNA in the ischemic hemisphere was up-regulated compared to the placebo stimulation group at the 7th and 14th day. At the 14th day a difference in motor function was observed in rats in the LFES group compared with the placebo stimulation group. Conclusion LFES can promote the proliferation of endogenous brain NSCs and the expression of bFGF and EGF in rats with acute cerebral infarction. It can also improve motor function and enhance neural plasticity in the brain.
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Objective To observe the effects of low frequency electrical nerve stimulation on sensory and motor functioning in patients with hemiplegia and hemianesthesia caused by acute cerebral infarction.Methods Sixty-one acute cerebral infarction patients with both hemiplegia and hemianesthesia were randomly divided into a treatment group and a control group.Thirty patients in the control group received conventional treatment.Thirty-one patients in the treatment group were treated with low frequency electrical stimulation of the peripheral nerves of the affected extremities in addition to the conventional treatment.Sensory function,motor function and performance in the activities of daily living(ADL)were evaluated before and 14 days after treatment.Results Sensory function,motor function and ADL performance in both groups improved significantly over the 14 days.Furthermore,the difference between the two groups after treatment was significant.Conclusion Low frequency electrical nerve stimulation can improve sensory function,motor function and ADL performance in acute cerebral infarction patients with both hemiplegia and hemianesthesia.
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Objective To study changes in synaptic plasticity in the contralesional mirror area of the cortexes of rats with cerebral infarction treated by low-frequency electrical stimulation(LFES)and to explore the therapeutic mechanism of LFES on the molecular level.Methods Forty-eight Sprague-Dawley rats were randomly allocated into a LFES group,a placebo group and a sham-operation group.Following middle cerebral artery occlusion(MCAO),rats in the LFES group were treated with LFES for 7 d(20 min/d),while the ones in placebo group were connected with the same LFES device but without electricity.Rats in the sham-operation group were subjected to a MCAO operation without occlusion and then received no special treatment.Synaptic ultra-structures and the expression levels of glia fibrillary acidic protein(CFAP)and synaptophysin in the contralesional mirror area of the cortexes of the rats in each group were measured with electron-microscopy and Western blotting.Results Compared with the placebo group or the rats before treatment,rats treated with LFES exhibited ultra-structural changes in the form of larger curvature of synaptic interfaces and narrower synaptic clefts.GFAP expression levels did not fluctuate significantly,but the expression of synaptophysin was significantly up-regulated.Conclusion LFES treatment can induce active changes in synaptic plasticity in the contralesional mirror area of the cortex of rats after cerebral infarction.
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OBJECTIVE: To investigate the effects of intramuscular low frequency electrical stimulation on shoulder pain in hemiplegic patients. METHOD: Twenty five hemiplegic shoulder pain patients were divided into two groups. For experimental group, we inserted stainless steel acupuncture needle on the motor points of supraspinatus, infraspinatus, trapezius and middle deltoid muscle and applied intramuscular electric stimulation (4 Hz, unsymmetric spike pulse, 2.0 ms of pulse width) for twenty minutes, three sessions a week, in total 10 sessions. For control group, we applied transcutaneous electrical nerve stimulation for twenty minutes. Visual analog scale(VAS), passive range of motion of shoulder joint, and Korean version of modified Barthel index (K-MBI) were measured before and after the treatment. RESULTS: The VAS of experimental group significantly decreased from 7.23+/-0.83 to 3.04+/-1.52, while control group showed a slight decrease from 7.50+/-0.70 to 5.64+/-0.74. The experimental group showed significant improvement compared to the control group (p<0.05). In the experimental group, there were significant improvements in motion of abduction from 103.6+/-20.5 to 134.0+/-32.3 and external rotation from 60.0+/-19.6 to 68.6+/-19.7 (p<0.05) even though there were no significant differences between the two groups. CONCLUSION: Intramuscular low frequency electrical stimulation improved pain as well as the range of motion. This could be used for the treatment of hemiplegic shoulder pain.
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Humans , Acupuncture , Deltoid Muscle , Electric Stimulation , Hemiplegia , Needles , Range of Motion, Articular , Shoulder , Shoulder Joint , Shoulder Pain , Stainless Steel , Transcutaneous Electric Nerve StimulationABSTRACT
@#Objective To observe the effect of transcranial low frequency electrical stimulation on the contents of monoamines in ischemic area of rats with middle cerebral artery occlusion(MCAO).MethodsPermanent MCAO model of Wistar rat was established with silk thread enveloped with polyammoniacum.The ischemic areas received various intensity of transcranial low frequency electrical stimulation for 1 hour in rats underwent 1 hour of ischemia.Then the affected tissue was processed with fluorospectrophotometry to determine the contents of dopamine(DA),noradrenalin(NE) and 5-hydroxytryptamine(5-HT).ResultsCompared with the sham-operation group,the contents of DA,NE and 5-HT in ischemic area of MCAO model rats decreased obviously(all P<0.01),while all three monoamines investigated in the sham-operation group with transcranial low frequency electrical stimulation had no significant change.In the MCAO groups stimulating with lower(10 V) and middle(30 V) intensity transcranial low frequency electrical field,the contents of DA,NE and 5-HT in ischemic area had no significant increase.But in the MCAO group stimulating with high(50 V) intensity transcranial low frequency electrical field,the contents of DA,NE and 5-HT in ischemic area increased significantly(P<0.05).ConclusionSome degree of intensity transcranial low frequency electrical field stimulation can increase the contents of DA,NE and 5-HT in ischemic area of rats subjected to MCAO.
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@#Objective To observe the effect of transcranial low frequency electrical stimulation on the contents of monoamines in ischemic area of rats with middle cerebral artery occlusion(MCAO).MethodsPermanent MCAO model of Wistar rat was established with silk thread enveloped with polyammoniacum.The ischemic areas received various intensity of transcranial low frequency electrical stimulation for 1 hour in rats underwent 1 hour of ischemia.Then the affected tissue was processed with fluorospectrophotometry to determine the contents of dopamine(DA),noradrenalin(NE) and 5-hydroxytryptamine(5-HT).ResultsCompared with the sham-operation group,the contents of DA,NE and 5-HT in ischemic area of MCAO model rats decreased obviously(all P<0.01),while all three monoamines investigated in the sham-operation group with transcranial low frequency electrical stimulation had no significant change.In the MCAO groups stimulating with lower(10 V) and middle(30 V) intensity transcranial low frequency electrical field,the contents of DA,NE and 5-HT in ischemic area had no significant increase.But in the MCAO group stimulating with high(50 V) intensity transcranial low frequency electrical field,the contents of DA,NE and 5-HT in ischemic area increased significantly(P<0.05).ConclusionSome degree of intensity transcranial low frequency electrical field stimulation can increase the contents of DA,NE and 5-HT in ischemic area of rats subjected to MCAO.
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Electrical stimulation is well used in medical therapeutics,but the mechanism still needs to be studied further. This paper applies an electrical stimulator to generate low frequency pulse,which is used to stimulate at the root of the thumb,right on the median nerve. EEGs were recorded before and after the stimulation. Comparing the EEGs changes between the former and latter using power spectral analysis,the effect of low frequency electrical stimulation on human nerve excitability is discussed.